Numerous vacuoles, often containing cytoplasmic contents in their structures, were observed in l-Nor-treated cells. triggered by l-Nor. The increase in cholesterol uptake as well as biosynthesis is not accompanied by an increase in cholesterol in the plasma membrane, but rather by aberrant build up in cytoplasmic compartments. We also found that cell death by l-Nor … Continue reading Numerous vacuoles, often containing cytoplasmic contents in their structures, were observed in l-Nor-treated cells